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Systems biology approaches for understanding cellular mechanisms of immunity in lymph nodes during infection

Adaptive immunity is initiated in secondary lymphoid tissues when naive T cells recognize foreign antigen presented as MHC-bound peptide on the surface of dendritic cells. Only a small fraction of T cells in the naive repertoire will express T cell receptors specific for a given epitope, but antigen...

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Dades bibliogràfiques
Publicat a:J Theor Biol
Autors principals: Mirsky, Henry Philip, Miller, Mark J., Linderman, Jennifer J., Kirschner, Denise E.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504675/
https://ncbi.nlm.nih.gov/pubmed/21798267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2011.06.037
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