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Single-domain antibodies for functional targeting of the signaling scaffold Shoc2
The accurate transmission of signals by the canonical ERK1/2 kinase pathway critically relies on the proper assembly of an intricate multiprotein complex by the scaffold protein Shoc2. However, the details of the mechanism by which Shoc2 guides ERK1/2 signals are not clear, in part, due to the lack...
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| Publicado en: | Mol Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6981032/ https://ncbi.nlm.nih.gov/pubmed/31869742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2019.12.010 |
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