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Exposure-based assessment of chemical teratogenicity using morphogenetic aggregates of human embryonic stem cells
Pluripotent stem cells recapitulate many aspects of embryogenesis in vitro. Here, we established a novel culture system to differentiate human embryonic stem cell aggregates (HESCA), and evaluated its utility for teratogenicity assessment. Culture of HESCA with modulators of developmental signals in...
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| Publicado no: | Reprod Toxicol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6980740/ https://ncbi.nlm.nih.gov/pubmed/31711903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2019.10.004 |
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