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Regulation of endoplasmic reticulum stress and trophectoderm lineage specification by the mevalonate pathway in the mouse preimplantation embryo

Early embryos are vulnerable to environmental insults, such as medications taken by the mother. Due to increasing prevalence of hypercholesterolemia, more women of childbearing potential are taking cholesterol-lowering medications called statins. Previously, we showed that inhibition of the mevalona...

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Détails bibliographiques
Publié dans:Mol Hum Reprod
Auteurs principaux: Marikawa, Yusuke, Menor, Mark, Deng, Youping, Alarcon, Vernadeth B
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990410/
https://ncbi.nlm.nih.gov/pubmed/33677573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gaab015
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