Increased activity of mesenchymal ALK2-BMP signaling causes posteriorly truncated microglossia and disorganization of lingual tissues

Proper development of taste organs including the tongue and taste papillae requires interactions with the underlying mesenchyme through multiple molecular signaling pathways. The effects of bone morphogenetic proteins (BMPs) and antagonists are profound, however, the tissue-specific roles of distinc...

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Bibliographic Details
Published in:Genesis
Main Authors: Ishan, Mohamed, Chen, Guiqian, Sun, Chenming, Chen, Shi-You, Komatsu, Yoshihiro, Mishina, Yuji, Liu, Hong-Xiang
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980365/
https://ncbi.nlm.nih.gov/pubmed/31571391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.23337
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