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Deploying Fluorescent Nucleoside Analogues for High Throughput Inhibitor Screening

High-throughput small molecule screening in drug discovery processes commonly rely on fluorescence-based methods including fluorescent polarization and fluorescence/Förster resonance energy transfer. These techniques use highly accessible instrumentation, however may suffer from high false negative...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chembiochem
Main Authors: Seebald, Leah, Madec, Amaël, Imperiali, Barbara
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980326/
https://ncbi.nlm.nih.gov/pubmed/31709708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900671
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