Fluorescence High-Throughput Screening for Inhibitors of TonB Action

Gram-negative bacteria acquire ferric siderophores through TonB-dependent outer membrane transporters (TBDT). By fluorescence spectroscopic hgh-throughput screening (FLHTS), we identified inhibitors of TonB-dependent ferric enterobactin (FeEnt) uptake through Escherichia coli FepA (EcoFepA). Among 1...

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Pubblicato in:J Bacteriol
Autori principali: Nairn, Brittany L., Eliasson, Olivia S., Hyder, Dallas R., Long, Noah J., Majumdar, Aritri, Chakravorty, Somnath, McDonald, Peter, Roy, Anuradha, Newton, Salete M., Klebba, Phillip E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405212/
https://ncbi.nlm.nih.gov/pubmed/28242720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00889-16
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