Universal fluorescent sensors of high-affinity iron transport, applied to ESKAPE pathogens

Sensitive assays of biochemical specificity, affinity, and capacity are valuable both for basic research and drug discovery. We created fluorescent sensors that monitor high-affinity binding reactions and used them to study iron acquisition by ESKAPE bacteria, which are frequently responsible for an...

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Vydáno v:J Biol Chem
Hlavní autoři: Chakravorty, Somnath, Shipelskiy, Yan, Kumar, Ashish, Majumdar, Aritri, Yang, Taihao, Nairn, Brittany L., Newton, Salete M., Klebba, Phillip E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Methods and Resources
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433069/
https://ncbi.nlm.nih.gov/pubmed/30679312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006921
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