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Identification of potential drugs for treatment of hepatic lipidosis in cats using an in vitro feline liver organoid system

BACKGROUND: Hepatic lipidosis is increasing in incidence in the Western world, with cats being particularly sensitive. When cats stop eating and start utilizing their fat reserves, free fatty acids (FFAs) increase in blood, causing an accumulation of triacylglycerol (TAG) in the liver. OBJECTIVE: Id...

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Bibliographic Details
Published in:J Vet Intern Med
Main Authors: Haaker, Maya W., Kruitwagen, Hedwig S., Vaandrager, Arie B., Houweling, Martin, Penning, Louis C., Molenaar, Martijn R., van Wolferen, Monique E., Oosterhoff, Loes A., Spee, Bart, Helms, J. Bernd
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Inc. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6979087/
https://ncbi.nlm.nih.gov/pubmed/31830357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvim.15670
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