ATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cells

Hepatic stellate cell (HSC) activation is a critical step in the development of chronic liver disease. During activation, HSCs lose their lipid droplets (LDs) containing triacylglycerol (TAG), cholesteryl esters (CEs), and retinyl esters (REs). Here we aimed to investigate which enzymes are involved...

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Détails bibliographiques
Publié dans:J Lipid Res
Auteurs principaux: Tuohetahuntila, Maidina, Molenaar, Martijn R., Spee, Bart, Brouwers, Jos F., Houweling, Martin, Vaandrager, Arie B., Helms, J. Bernd
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2016
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918846/
https://ncbi.nlm.nih.gov/pubmed/27179362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M066415
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