Replacement of Retinyl Esters by Polyunsaturated Triacylglycerol Species in Lipid Droplets of Hepatic Stellate Cells during Activation

Activation of hepatic stellate cells has been recognized as one of the first steps in liver injury and repair. During activation, hepatic stellate cells transform into myofibroblasts with concomitant loss of their lipid droplets (LDs) and production of excessive extracellular matrix. Here we aimed t...

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Main Authors: Testerink, Nicole, Ajat, Mokrish, Houweling, Martin, Brouwers, Jos F., Pully, Vishnu V., van Manen, Henk-Jan, Otto, Cees, Helms, J. Bernd, Vaandrager, Arie B.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335019/
https://ncbi.nlm.nih.gov/pubmed/22536341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034945
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