Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis

Hepatic steatosis is a highly prevalent liver disease, yet research is hampered by the lack of tractable cellular and animal models. Steatosis also occurs in cats, where it can cause severe hepatic failure. Previous studies demonstrate the potential of liver organoids for modeling genetic diseases....

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Vydáno v:Stem Cell Reports
Hlavní autoři: Kruitwagen, Hedwig S., Oosterhoff, Loes A., Vernooij, Ingrid G.W.H., Schrall, Ingrid M., van Wolferen, Monique E., Bannink, Farah, Roesch, Camille, van Uden, Lisa, Molenaar, Martijn R., Helms, J. Bernd, Grinwis, Guy C.M., Verstegen, Monique M.A., van der Laan, Luc J.W., Huch, Meritxell, Geijsen, Niels, Vries, Robert G., Clevers, Hans, Rothuizen, Jan, Schotanus, Baukje A., Penning, Louis C., Spee, Bart
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
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Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390114/
https://ncbi.nlm.nih.gov/pubmed/28344000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.02.015
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