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Factor VIII: Perspectives on Immunogenicity and Tolerogenic Strategies

Therapeutic treatment of bleeds with FVIII can lead to an antibody response that effectively inhibits its function. Herein, we review the factors that contribute to this immunogenicity and possible ways to overcome it.

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Scott, David W., Pratt, Kathleen P.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978909/
https://ncbi.nlm.nih.gov/pubmed/32010137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03078
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