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Factor VIII: Perspectives on Immunogenicity and Tolerogenic Strategies

Therapeutic treatment of bleeds with FVIII can lead to an antibody response that effectively inhibits its function. Herein, we review the factors that contribute to this immunogenicity and possible ways to overcome it.

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Scott, David W., Pratt, Kathleen P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978909/
https://ncbi.nlm.nih.gov/pubmed/32010137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03078
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