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Factor VIII: Perspectives on Immunogenicity and Tolerogenic Strategies

Therapeutic treatment of bleeds with FVIII can lead to an antibody response that effectively inhibits its function. Herein, we review the factors that contribute to this immunogenicity and possible ways to overcome it.

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Scott, David W., Pratt, Kathleen P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978909/
https://ncbi.nlm.nih.gov/pubmed/32010137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03078
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