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Factor VIII: Perspectives on Immunogenicity and Tolerogenic Strategies

Therapeutic treatment of bleeds with FVIII can lead to an antibody response that effectively inhibits its function. Herein, we review the factors that contribute to this immunogenicity and possible ways to overcome it.

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Scott, David W., Pratt, Kathleen P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978909/
https://ncbi.nlm.nih.gov/pubmed/32010137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03078
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