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Progress toward inducing immunologic tolerance to factor VIII

A major problem in treating hemophilia A patients with therapeutic factor VIII (FVIII) is that 20% to 30% of these patients produce neutralizing anti-FVIII antibodies. These antibodies block (inhibit) the procoagulant function of FVIII and thus are termed “inhibitors.” The currently accepted clinica...

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Detalhes bibliográficos
Main Authors: Scott, David W., Pratt, Kathleen P., Miao, Carol H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668484/
https://ncbi.nlm.nih.gov/pubmed/23502223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-01-478669
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