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Progress toward inducing immunologic tolerance to factor VIII
A major problem in treating hemophilia A patients with therapeutic factor VIII (FVIII) is that 20% to 30% of these patients produce neutralizing anti-FVIII antibodies. These antibodies block (inhibit) the procoagulant function of FVIII and thus are termed “inhibitors.” The currently accepted clinica...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society of Hematology
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668484/ https://ncbi.nlm.nih.gov/pubmed/23502223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-01-478669 |
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