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Opioids Impair Intestinal Epithelial Repair in HIV-Infected Humanized Mice

Intestinal barrier dysfunction and subsequent microbial translocation play crucial roles in persistent immune activation leading to HIV disease progression. Opioid use is associated with worse outcome in HIV-infected patients. The exacerbated disease progression by opioids is mainly driven by excess...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Meng, Jingjing, Banerjee, Santanu, Zhang, Li, Sindberg, Greg, Moidunny, Shamsudheen, Li, Bin, Robbins, David J., Girotra, Mohit, Segura, Bradley, Ramakrishnan, Sundaram, Roy, Sabita
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978907/
https://ncbi.nlm.nih.gov/pubmed/32010125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02999
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