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Opioid Exacerbation of Gram-positive sepsis, induced by Gut Microbial Modulation, is Rescued by IL-17A Neutralization

Sepsis is the predominant cause of mortality in ICUs, and opioids are the preferred analgesic in this setting. However, the role of opioids in sepsis progression has not been well characterized. The present study demonstrated that morphine alone altered the gut microbiome and selectively induced the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Meng, Jingjing, Banerjee, Santanu, Li, Dan, Sindberg, Gregory M., Wang, Fuyuan, Ma, Jing, Roy, Sabita
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454150/
https://ncbi.nlm.nih.gov/pubmed/26039416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10918
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