Direct Quantification of Damaged Nucleotides in Oligonucleotides Using an Aerolysin Single Molecule Interface

[Image: see text] DNA lesions such as metholcytosine((m)C), 8-OXO-guanine ((O)G), inosine (I), etc. could cause genetic diseases. Identification of the varieties of lesion bases are usually beyond the capability of conventional DNA sequencing which is mainly designed to discriminate four bases only....

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Foilsithe in:ACS Cent Sci
Main Authors: Wang, Jiajun, Li, Meng-Yin, Yang, Jie, Wang, Ya-Qian, Wu, Xue-Yuan, Huang, Jin, Ying, Yi-Lun, Long, Yi-Tao
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2020
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978832/
https://ncbi.nlm.nih.gov/pubmed/31989027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b01129
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