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Revealing the transient conformations of a single flavin adenine dinucleotide using an aerolysin nanopore

Flavin adenine dinucleotide (FAD) as a cofactor is involved in numerous important metabolic pathways where the biological function is intrinsically related to its transient conformations. The confined space of enzymes requires FAD set in its specific intermediate conformation. However, conventional...

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Vydáno v:Chem Sci
Hlavní autoři: Li, Meng-Yin, Wang, Ya-Qian, Ying, Yi-Lun, Long, Yi-Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988595/
https://ncbi.nlm.nih.gov/pubmed/32110330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03163d
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