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A lithium-ion-active aerolysin nanopore for effectively trapping long single-stranded DNA

Wild-type aerolysin (AeL) nanopores allow direct single nucleotide discrimination of very short oligonucleotides (≤10 nt) without labelling, which shows great potential for DNA sensing. To achieve real applications, one major obstacle of AeL is its poor capture ability of long single-stranded DNA (s...

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Foilsithe in:Chem Sci
Main Authors: Hu, Zheng-Li, Li, Meng-Yin, Liu, Shao-Chuang, Ying, Yi-Lun, Long, Yi-Tao
Formáid: Artigo
Teanga:Inglês
Foilsithe: Royal Society of Chemistry 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334748/
https://ncbi.nlm.nih.gov/pubmed/30746084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc03927e
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