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Inhibitory effect of alpinetin on IL‐6 expression by promoting cytosine methylation in CpG islands in the IL‐6 promoter region

BACKGROUND: Alpinetin is a flavonoid which exerts antibacterial and anti‐inflammatory functions. In order to prove that the induced methylation is an important mechanism for alpinetin in regulating the expression of inflammatory factor Interleukin‐6 (IL‐6), we detected the dinucleotide methylation s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Genet Genomic Med
Hauptverfasser: Hu, Ke, Li, Yuxian, Liang, Minghua, Liu, Lijing, Chen, Yuefu, Huang, Minjiang, Tan, Bifeng, Luo, Yingquan, Yin, Huiming
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978396/
https://ncbi.nlm.nih.gov/pubmed/31724331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.993
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