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Inhibitory effect of alpinetin on IL‐6 expression by promoting cytosine methylation in CpG islands in the IL‐6 promoter region

BACKGROUND: Alpinetin is a flavonoid which exerts antibacterial and anti‐inflammatory functions. In order to prove that the induced methylation is an important mechanism for alpinetin in regulating the expression of inflammatory factor Interleukin‐6 (IL‐6), we detected the dinucleotide methylation s...

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Dades bibliogràfiques
Publicat a:Mol Genet Genomic Med
Autors principals: Hu, Ke, Li, Yuxian, Liang, Minghua, Liu, Lijing, Chen, Yuefu, Huang, Minjiang, Tan, Bifeng, Luo, Yingquan, Yin, Huiming
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978396/
https://ncbi.nlm.nih.gov/pubmed/31724331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.993
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