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Special vulnerability of somatic niche cells to transposable element activation in Drosophila larval ovaries

In the Drosophila ovary, somatic escort cells (ECs) form a niche that promotes differentiation of germline stem cell (GSC) progeny. The piRNA (Piwi-interacting RNA) pathway, which represses transposable elements (TEs), is required in ECs to prevent the accumulation of undifferentiated germ cells (ge...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sokolova, Olesya A., Mikhaleva, Elena A., Kharitonov, Sergey L., Abramov, Yuri A., Gvozdev, Vladimir A., Klenov, Mikhail S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978372/
https://ncbi.nlm.nih.gov/pubmed/31974416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57901-2
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