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Separation of stem cell maintenance and transposon silencing functions of Piwi protein

Piwi-interacting RNAs (piRNAs) and Piwi proteins have the evolutionarily conserved function of silencing of repetitive genetic elements in germ lines. The founder of the Piwi subfamily, Drosophila nuclear Piwi protein, was also shown to be required for the maintenance of germ-line stem cells (GSCs)....

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Detalhes bibliográficos
Principais autores: Klenov, Mikhail S., Sokolova, Olesya A., Yakushev, Evgeny Y., Stolyarenko, Anastasia D., Mikhaleva, Elena A., Lavrov, Sergey A., Gvozdev, Vladimir A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219103/
https://ncbi.nlm.nih.gov/pubmed/22065765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106676108
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