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Regulation of hippocampal neuronal apoptosis and autophagy in mice with sepsis‐associated encephalopathy by immunity‐related GTPase M1

AIMS: Sepsis‐associated encephalopathy (SAE) is a common complication of severe sepsis. Our goal was to investigate the role of immunity‐related GTPase M1 (IRGM1) in SAE and its underlying mechanism. METHODS: A mouse sepsis model was established by cecal ligation and perforation. SAE was diagnosed b...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Zhou, Rui‐Xi, Li, Yu‐Yao, Qu, Yi, Huang, Qun, Sun, Xue‐Mei, Mu, De‐Zhi, Li, Xi‐Hong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978258/
https://ncbi.nlm.nih.gov/pubmed/31612615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13229
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