Concordance for clonal hematopoiesis is limited in elderly twins

Although acquisition of leukemia-associated somatic mutations by 1 or more hematopoietic stem cells is inevitable with advancing age, its consequences are highly variable, ranging from clinically silent clonal hematopoiesis (CH) to leukemic progression. To investigate the influence of heritable fact...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Fabre, Margarete A., McKerrell, Thomas, Zwiebel, Maximillian, Vijayabaskar, M. S., Park, Naomi, Wells, Philippa M., Rad, Roland, Deloukas, Panagiotis, Small, Kerrin, Steves, Claire J., Vassiliou, George S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978156/
https://ncbi.nlm.nih.gov/pubmed/31697828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001807
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