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Concomitant memantine and Lactobacillus plantarum treatment attenuates cognitive impairments in APP/PS1 mice

Trimethylamine-N-oxide (TMAO) is a gut microbial metabolite that promotes Alzheimer’s disease (AD) progression. Given that probiotics can alleviate AD symptoms by inhibiting the synthesis of TMAO, here we investigated the correlation between TMAO and cognitive deterioration by measuring TMAO levels...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Wang, Qiu-Jun, Shen, Yue-E, Wang, Xin, Fu, Shuang, Zhang, Xin, Zhang, Yi-Na, Wang, Rui-Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977692/
https://ncbi.nlm.nih.gov/pubmed/31907339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102645
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