Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice

BACKGROUND: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by an abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation, and impaired neurogenesis. Urolithin A (UA), a gut-microbial metabolite of ellagic acid, has been reported to exert anti-inflammato...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Gong, Zhuo, Huang, Jingyi, Xu, Biao, Ou, Zhenri, Zhang, Le, Lin, Xiaohong, Ye, Xiujuan, Kong, Xuejian, Long, Dahong, Sun, Xiangdong, He, Xiaosong, Xu, Liping, Li, Qingqing, Xuan, Aiguo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417212/
https://ncbi.nlm.nih.gov/pubmed/30871577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1450-3
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