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Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein
Alzheimer’s disease (AD) is the most prevalent type of dementia. Down syndrome (DS) is the leading genetic risk factor for Early-Onset AD, prematurely presenting the classic pathological features of the brain with AD. Augmented gene dosage, including the APP gene, could partially cause this predispo...
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| Publicado no: | Aging (Albany NY) |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6977673/ https://ncbi.nlm.nih.gov/pubmed/31918411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102677 |
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