Metabolic and Genetic Determinants of Glucose Shape After Oral Challenge in Obese Youths: A Longitudinal Study

CONTEXT: The time-to-glucose-peak following the oral glucose tolerance test (OGTT) is a highly reproducible marker for diabetes risk. In obese youths, we lack evidence for the mechanisms underlying the effects of the TCF7L2 rs7903146 variant on glucose peak. METHODS: We analyzed the metabolic phenot...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Galderisi, Alfonso, Tricò, Domenico, Dalla Man, Chiara, Santoro, Nicola, Pierpont, Bridget, Groop, Leif, Cobelli, Claudio, Caprio, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977541/
https://ncbi.nlm.nih.gov/pubmed/31972003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgz207
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