טוען...
Ureidopeptide GLP-1 analogues with prolonged activity in vivo via signal bias and altered receptor trafficking
The high demand of the pharmaceutical industry for new modalities to address the diversification of biological targets with large surfaces of interaction led us to investigate the replacement of α-amino acid residues with ureido units at selected positions in peptides to improve potency and generate...
שמור ב:
| הוצא לאור ב: | Chem Sci |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Royal Society of Chemistry
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6977461/ https://ncbi.nlm.nih.gov/pubmed/32015811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc02079a |
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