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Blockade of IL-6 signaling prevents paclitaxel-induced neuropathy in C57Bl/6 mice
The microtubule-stabilizing agent paclitaxel frequently leads to chemotherapy-induced peripheral neuropathy (CIN), which further increases the burden of disease and often necessitates treatment limitations. The pathophysiology of CIN appears to involve both “upstream” effects including altered intra...
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| Pubblicato in: | Cell Death Dis |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6976596/ https://ncbi.nlm.nih.gov/pubmed/31969555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2239-0 |
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