Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors

N-Methyl-D-aspartate receptors (NMDARs) play critical roles in the central nervous system. Their heterotetrameric composition generates subtypes with distinct functional properties and spatio-temporal distribution in the brain, raising the possibility for subtype-specific targeting by pharmacologica...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Wang, Jue Xiang, Irvine, Mark W., Burnell, Erica S., Sapkota, Kiran, Thatcher, Robert J., Li, Minjun, Simorowski, Noriko, Volianskis, Arturas, Collingridge, Graham L., Monaghan, Daniel T., Jane, David E., Furukawa, Hiro
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976569/
https://ncbi.nlm.nih.gov/pubmed/31969570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14321-0
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