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S-nitrosylation of connexin43 hemichannels elicits cardiac stress–induced arrhythmias in Duchenne muscular dystrophy mice

Patients with Duchenne muscular dystrophy (DMD) commonly present with severe ventricular arrhythmias that contribute to heart failure. Arrhythmias and lethality are also consistently observed in adult Dmd(mdx) mice, a mouse model of DMD, after acute β-adrenergic stimulation. These pathological featu...

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Podrobná bibliografie
Vydáno v:JCI Insight
Hlavní autoři: Lillo, Mauricio A., Himelman, Eric, Shirokova, Natalia, Xie, Lai-Hua, Fraidenraich, Diego, Contreras, Jorge E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975272/
https://ncbi.nlm.nih.gov/pubmed/31751316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130091
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