Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy

Aberrant expression of the cardiac gap junction protein connexin-43 (Cx43) has been suggested as playing a role in the development of cardiac disease in the mdx mouse model of Duchenne muscular dystrophy (DMD); however, a mechanistic understanding of this association is lacking. Here, we identified...

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Pubblicato in:J Clin Invest
Autori principali: Himelman, Eric, Lillo, Mauricio A., Nouet, Julie, Gonzalez, J. Patrick, Zhao, Qingshi, Xie, Lai-Hua, Li, Hong, Liu, Tong, Wehrens, Xander H.T., Lampe, Paul D., Fishman, Glenn I., Shirokova, Natalia, Contreras, Jorge E., Fraidenraich, Diego
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108916/
https://ncbi.nlm.nih.gov/pubmed/31910160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128190
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