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Next generation sequencing as second-tier test in high-throughput newborn screening for nephropathic cystinosis

Nephropathic cystinosis is a rare autosomal recessive lysosomal storage disorder, which causes loss of renal proximal tubular function and progressive loss of glomerular function, finally leading to end stage renal failure at school age. In the course of the disease most patients will need kidney tr...

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Détails bibliographiques
Publié dans:Eur J Hum Genet
Auteurs principaux: Fleige, Tobias, Burggraf, Siegfried, Czibere, Ludwig, Häring, Julia, Glück, Birgit, Keitel, Lisa Marie, Landt, Olfert, Harms, Erik, Hohenfellner, Katharina, Durner, Jürgen, Röschinger, Wulf, Becker, Marc
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974606/
https://ncbi.nlm.nih.gov/pubmed/31570786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-019-0521-3
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