Validation studies for germ-free Smad3(-/-) mice as a bio-assay to test the causative role of fecal microbiomes in IBD

While the association between microbiomes and inflammatory bowel disease (IBD) is well known, establishing causal relationships between the two is difficult in humans. Germ-free (GF) mice genetically susceptible to IBD can address this question. Smad3(-/-) mice with defective transforming growth fac...

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Enregistré dans:
Détails bibliographiques
Publié dans:Gut Microbes
Auteurs principaux: Paik, Jisun, Meeker, Stacey, Hsu, Charlie C., Seamons, Audrey, Pershutkina, Olesya, Snyder, Jessica M., Brabb, Thea, Maggio-Price, Lillian
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2019
Sujets:
Brief Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973324/
https://ncbi.nlm.nih.gov/pubmed/31138018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19490976.2019.1611151
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