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Validation studies for germ-free Smad3(-/-) mice as a bio-assay to test the causative role of fecal microbiomes in IBD

While the association between microbiomes and inflammatory bowel disease (IBD) is well known, establishing causal relationships between the two is difficult in humans. Germ-free (GF) mice genetically susceptible to IBD can address this question. Smad3(-/-) mice with defective transforming growth fac...

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Detalhes bibliográficos
Publicado no:Gut Microbes
Main Authors: Paik, Jisun, Meeker, Stacey, Hsu, Charlie C., Seamons, Audrey, Pershutkina, Olesya, Snyder, Jessica M., Brabb, Thea, Maggio-Price, Lillian
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973324/
https://ncbi.nlm.nih.gov/pubmed/31138018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19490976.2019.1611151
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