Validation studies for germ-free Smad3(-/-) mice as a bio-assay to test the causative role of fecal microbiomes in IBD

While the association between microbiomes and inflammatory bowel disease (IBD) is well known, establishing causal relationships between the two is difficult in humans. Germ-free (GF) mice genetically susceptible to IBD can address this question. Smad3(-/-) mice with defective transforming growth fac...

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Detalles Bibliográficos
Publicado en:Gut Microbes
Main Authors: Paik, Jisun, Meeker, Stacey, Hsu, Charlie C., Seamons, Audrey, Pershutkina, Olesya, Snyder, Jessica M., Brabb, Thea, Maggio-Price, Lillian
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
Assuntos:
Brief Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973324/
https://ncbi.nlm.nih.gov/pubmed/31138018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19490976.2019.1611151
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