Allfudo'n Llwyddiannus — 
Llwytho...

High‐throughput compound screen reveals mTOR inhibitors as potential therapeutics to reduce (auto)antibody production by human plasma cells

Antibody production by the B cell compartment is a crucial part of the adaptive immune response. Dysregulated antibody production in the form of autoantibodies can cause autoimmune disease. To date, B‐cell depletion with anti‐CD20 antibodies is commonly applied in autoimmunity, but pre‐existing plas...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Eur J Immunol
Prif Awduron: Tuijnenburg, Paul, aan de Kerk, Daan J., Jansen, Machiel H., Morris, Ben, Lieftink, Cor, Beijersbergen, Roderick L., van Leeuwen, Ester M.M., Kuijpers, Taco W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972998/
https://ncbi.nlm.nih.gov/pubmed/31621069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948241
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!