Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1

Establishing gene regulatory networks during differentiation or reprogramming requires master or pioneer transcription factors (TFs) such as PU.1, a prototype master TF of hematopoietic lineage differentiation. To systematically determine molecular features that control its activity, here we analyze...

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Published in:Nat Commun
Main Authors: Minderjahn, Julia, Schmidt, Andreas, Fuchs, Andreas, Schill, Rudolf, Raithel, Johanna, Babina, Magda, Schmidl, Christian, Gebhard, Claudia, Schmidhofer, Sandra, Mendes, Karina, Ratermann, Anna, Glatz, Dagmar, Nützel, Margit, Edinger, Matthias, Hoffman, Petra, Spang, Rainer, Längst, Gernot, Imhof, Axel, Rehli, Michael
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972792/
https://ncbi.nlm.nih.gov/pubmed/31964861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13960-2
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