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Bayesian model selection for the study of Hardy–Weinberg proportions and homogeneity of gender allele frequencies

Standard statistical tests for Hardy–Weinberg equilibrium assume the equality of allele frequencies in the sexes, whereas tests for the equality of allele frequencies in the sexes assume Hardy–Weinberg equilibrium. This produces a circularity in the testing of genetic variants, which has recently be...

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Bibliografiske detaljer
Udgivet i:Heredity (Edinb)
Main Authors: Puig, Xavier, Ginebra, Josep, Graffelman, Jan
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972714/
https://ncbi.nlm.nih.gov/pubmed/31142813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41437-019-0232-0
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