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Statistical Inference for Hardy-Weinberg Proportions in the Presence of Missing Genotype Information
In genetic association studies, tests for Hardy-Weinberg proportions are often employed as a quality control checking procedure. Missing genotypes are typically discarded prior to testing. In this paper we show that inference for Hardy-Weinberg proportions can be biased when missing values are disca...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3877411/ https://ncbi.nlm.nih.gov/pubmed/24391752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083316 |
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