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Bayesian model selection for the study of Hardy–Weinberg proportions and homogeneity of gender allele frequencies

Standard statistical tests for Hardy–Weinberg equilibrium assume the equality of allele frequencies in the sexes, whereas tests for the equality of allele frequencies in the sexes assume Hardy–Weinberg equilibrium. This produces a circularity in the testing of genetic variants, which has recently be...

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Detalhes bibliográficos
Publicado no:Heredity (Edinb)
Main Authors: Puig, Xavier, Ginebra, Josep, Graffelman, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972714/
https://ncbi.nlm.nih.gov/pubmed/31142813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41437-019-0232-0
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