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Iron‐Mediated Electrophilic Amination of Organozinc Halides using Organic Azides

A wide range of alkyl‐, aryl‐ and heteroarylzinc halides were aminated with highly functionalized alkyl, aryl, and heterocyclic azides. The reaction proceeds smoothly at 50 °C within 1 h in the presence of FeCl(3) (0.5 equiv) to furnish the corresponding secondary amines in good yields. This method...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Graßl, Simon, Singer, Johannes, Knochel, Paul
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972526/
https://ncbi.nlm.nih.gov/pubmed/31599056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201911704
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