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Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model

Tuberculous meningitis (TBM) is the most devastating form of extrapulmonary Mycobacterium tuberculosis infection in humans. Severe inflammation and extensive tissue damage drive the morbidity and mortality of this manifestation of tuberculosis (TB). Antibiotic treatment is ineffective at curing TBM...

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Bibliografiske detaljer
Udgivet i:Front Cell Infect Microbiol
Main Authors: Kumar, Ranjeet, Kolloli, Afsal, Singh, Pooja, Vinnard, Christopher, Kaplan, Gilla, Subbian, Selvakumar
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972508/
https://ncbi.nlm.nih.gov/pubmed/32010638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00450
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