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Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model

Tuberculous meningitis (TBM) is the most devastating form of extrapulmonary Mycobacterium tuberculosis infection in humans. Severe inflammation and extensive tissue damage drive the morbidity and mortality of this manifestation of tuberculosis (TB). Antibiotic treatment is ineffective at curing TBM...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Kumar, Ranjeet, Kolloli, Afsal, Singh, Pooja, Vinnard, Christopher, Kaplan, Gilla, Subbian, Selvakumar
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972508/
https://ncbi.nlm.nih.gov/pubmed/32010638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00450
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