Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model

Tuberculous meningitis (TBM) is the most devastating form of extrapulmonary Mycobacterium tuberculosis infection in humans. Severe inflammation and extensive tissue damage drive the morbidity and mortality of this manifestation of tuberculosis (TB). Antibiotic treatment is ineffective at curing TBM...

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Bibliografische gegevens
Gepubliceerd in:Front Cell Infect Microbiol
Hoofdauteurs: Kumar, Ranjeet, Kolloli, Afsal, Singh, Pooja, Vinnard, Christopher, Kaplan, Gilla, Subbian, Selvakumar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Cellular and Infection Microbiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972508/
https://ncbi.nlm.nih.gov/pubmed/32010638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00450
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