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Sec translocon has an insertase-like function in addition to polypeptide conduction through the channel

The Sec translocon provides a polypeptide-conducting channel, which is insulated from the hydrophobic lipidic environment of the membrane, for translocation of hydrophilic passenger polypeptides. Its lateral gate allows a downstream hydrophobic segment (stop-transfer sequence) to exit the channel la...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Ito, Koreaki, Shimokawa-Chiba, Naomi, Chiba, Shinobu
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971846/
https://ncbi.nlm.nih.gov/pubmed/32025287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.21065.1
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