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Hydrophilic microenvironment required for the channel-independent insertase function of YidC protein
The recently solved crystal structure of YidC protein suggests that it mediates membrane protein insertion by means of an intramembrane cavity rather than a transmembrane (TM) pore. This concept of protein translocation prompted us to characterize the native, membrane-integrated state of YidC with r...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4413333/ https://ncbi.nlm.nih.gov/pubmed/25855636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423817112 |
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